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C0478

Sigma-Aldrich

Anti-Calpain LP-85 (Lens-Specific Calpain) (Domain IV), Large Subunit antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

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About This Item

MDL number:
UNSPSC Code:
12352203

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

mouse, rat

concentration

~1 mg/mL

technique(s)

western blot: 1:1,000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

mouse ... Capn3(12335)
rat ... Capn3(29155)

Specificity

By immunoblotting against the reduced protein, the antibody reacts with bands at 85 kDa and 62 kDa and a series of further cleaved active forms. It also reacts with non-reduced calpain LP-85. The antibody does not cross-react with other calpain family members (calpain LP-82, μ-calpain, m-calpain, calpain-94, ncl-2, ncl-3, etc.).

Immunogen

synthetic peptide corresponding to a unique insert found in the ELF-hand (the calcium binding domain-IV in the large subunit) of rat LP-85 calpain (lens-specific calpain).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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