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Key Documents

C0224

Sigma-Aldrich

Monoclonal Anti-Cdc6 antibody produced in mouse

clone DCS-180, ascites fluid

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About This Item

MDL number:
MFCD02096042
UNSPSC Code:
12352203

biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

DCS-180, monoclonal

mol wt

antigen 62 kDa

contains

15 mM sodium azide

species reactivity

human

technique(s)

immunoprecipitation (IP): suitable
microarray: suitable
western blot: 1:2,000 using a HeLa cell extract

isotype

IgG1

UniProt accession no.

Q99741

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... CDC6(990)

Immunogen

recombinant human Cdc6

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Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Certificates of Analysis (COA)

Lot/Batch Number
049H4861

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Philippe Coulombe et al.
Nature communications, 10(1), 2426-2426 (2019-06-05)
DNA replication initiation is a two-step process. During the G1-phase of the cell cycle, the ORC complex, CDC6, CDT1, and MCM2-7 assemble at replication origins, forming pre-replicative complexes (pre-RCs). In S-phase, kinase activities allow fork establishment through (CDC45/MCM2-7/GINS) CMG-complex formation.

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