B9803
Bone Morphogenetic Protein 5 human
recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture, >95% (SDS-PAGE)
Synonym(s):
BMP-5
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About This Item
MDL number:
UNSPSC Code:
51111800
Recommended Products
biological source
human
recombinant
expressed in NSO cells
assay
>95% (SDS-PAGE)
form
lyophilized powder
mol wt
subunit calculated mol wt ~18 kDa
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... BMP5(653)
Biochem/physiol Actions
Cellular responses to BMP-5 is mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors.
Physical form
Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile, 0.1% TFA, with 5% trehalose and 50 μg of BSA per 1 μg of cytokine
Analysis Note
The biological activity is measured by its ability to induce alkaline phosphatase production in ATDC5 chondrogenic cells.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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T Ebendal et al.
Journal of neuroscience research, 51(2), 139-146 (1998-02-20)
Transforming growth factors-beta (TGF-betas), activins, and bone morphogenetic proteins (BMPs) comprise an evolutionarily well-conserved group of proteins controlling a number of cell differentiation, cell growth, and morphogentic processes during development. The superfamily of TGFbeta-related genes include over 25 members in
A H Reddi
Nature biotechnology, 16(3), 247-252 (1998-04-07)
Morphogenesis is the developmental cascade of pattern formation and body plan establishment, culminating in the adult form. It has formed the basis for the emerging discipline of tissue engineering, which uses principles of molecular developmental biology and morphogenesis gleaned through
M Kawabata et al.
Cytokine & growth factor reviews, 9(1), 49-61 (1998-08-28)
Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which are members of the transforming growth factor-beta (TGF-beta) superfamily. Activities of BMPs are extracellularly regulated by BMP-binding proteins, Noggin and Chordin. BMPs bind to two different types of serine-threonine kinase receptors, type
Elina V García et al.
Theriogenology, 84(4), 589-599 (2015-05-28)
Previous studies have reported that bone morphogenetic protein 5 (BMP5) is differentially expressed in the isthmus of bovine oviducts and it is present in the oviductal fluid. However, the specific action of this factor is unknown. To evaluate whether BMP5
Zhu Xishan et al.
Journal of experimental & clinical cancer research : CR, 30, 47-47 (2011-05-04)
Overwhelming evidence from leukemia research has shown that the clonal population of neoplastic cells exhibits marked heterogeneity with respect to proliferation and differentiation. There are rare stem cells within the leukemic population that possess extensive proliferation and self-renewal capacity not
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