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B5400

Sigma-Aldrich

Butyl p-aminobenzoate–Agarose

buffered aqueous suspension

Synonym(s):

Butesin agarose

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About This Item

MDL number:
MFCD00163180
UNSPSC Code:
23151817
NACRES:
NA.56

form

buffered aqueous suspension

extent of labeling

150-250 μmol per mL

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

capacity

1-3 mg/mL binding capacity (plasminogen)

storage temp.

2-8°C

Application

Butyl p-aminobenzoate-agarose is an agarose conjugate in buffered aqueous suspension used in affinity chromatography, protein chromatography and hydrophobic interaction methodologies. Butyl p-aminobenzoate-agarose has been used in studies to assess local anesthetic inhibition and activity of human serum albumin.

Physical form

Suspension in 0.05 M NaHCO3, 0.5 M NaCl, pH 8.0, containing preservative

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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D L B Winkelman et al.
The Journal of pharmacology and experimental therapeutics, 314(3), 1177-1186 (2005-06-01)
n-Butyl-p-aminobenzoate (BAB; butamben) is a long-duration anesthetic used for the treatment of chronic pain. Epidural administration of BAB is thought to reduce the electrical excitability of dorsal root nociceptor fibers by inhibiting voltage-gated ion channels. To further investigate this mechanism
Shen-Feng Ma et al.
Drug metabolism and disposition: the biological fate of chemicals, 33(12), 1911-1919 (2005-09-27)
In the present study, we investigated the esterase-like activity of human serum albumin (HSA) and the mechanism by which it hydrolyzes, and thereby activates, olmesartan medoxomil (CS-866), a novel angiotensin II receptor antagonist. CS-866 has previously been shown to be
Laurentius J A Rampaart et al.
Anesthesia and analgesia, 106(6), 1778-1783 (2008-05-24)
Butamben or n-butyl-p-aminobenzoate is a long-acting experimental local anesthetic for the treatment of chronic pain when given as an epidural suspension. We have investigated whether Cav1.2/L-type calcium channels may be a target of this butamben action. The effect of butamben

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