B3935

Monoclonal Anti-Bone Morphogenetic Protein 8 antibody produced in mouse

clone 158708, purified immunoglobulin, lyophilized powder

• Synonym(s): Anti-BMP-8
• MDL number: MFCD06798698
• UNSPSC Code: 51111800
• NACRES: NA.41

Properties

• biological source: mouse
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 158708, monoclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): indirect ELISA: 0.5-1.0 μg/mL; western blot: 1-2 μg/mL
• isotype: IgG2b
• UniProt accession no.: P34820
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... BMP8B(656)

Description

General description

The anibody shows no cross-reactivity with recombinant human BMP-2, BMP-3, BMP-4, BMP-5, BMP-6, or BMP-7.

Immunogen

purified, E. coli-derived, recombinant mature human bone morphogenetic protein 8.

Biochem/physiol Actions

Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)