We have not found this to be suitable for PCR. This product is soluble in water (50 mg/ml), yielding a clear, colorless solution. The solubility of this product in water has also been reported at 64.7 g/100ml (25 °C). It is soluble at 5.0 g/100 mL in ethanol. It is practically insoluble in chloroform and in ether. The pH of a 5% aqueous solution of this product is 1.0
B3501
Betaine hydrochloride
≥99%
Synonym(s):
(Carboxymethyl)trimethylammonium hydrochloride
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100 G
$27.20
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$46.80
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$143.00
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100 G
$27.20
250 G
$46.80
1 KG
$143.00
About This Item
Linear Formula:
(CH3)3N+CH2COOH · Cl-
CAS Number:
Molecular Weight:
153.61
Beilstein/REAXYS Number:
3916181
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
biological source
synthetic (organic)
Quality Level
assay
≥99%
form
powder or crystals
mp
241-242 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless
storage temp.
room temp
SMILES string
[Cl-].C[N+](C)(C)CC(O)=O
InChI
1S/C5H11NO2.ClH/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H
InChI key
HOPSCVCBEOCPJZ-UHFFFAOYSA-N
Gene Information
human ... BHMT(635) , BHMT2(23743)
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General description
Application
Betaine hydrochloride has been used as a component of fixative in HEPES or cacodylate buffer to improve preservation of the ultrastructural morphology of human spermatozoa.[3]
Biochem/physiol Actions
Betaine hydrochloride can decrease hepatotoxicity, that is stimulated by ethanol.[1]
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.[4]
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Hi! I have two questions about betaine hydrochloride: 1. Can it be used in PCR like betaine?; 2. Why is it hard to dissolve at 5M, and how can I fix this? Thanks for your help!
1 answer-
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