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B1309

Sigma-Aldrich

BCMA/Fc Chimera from mouse

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym(s):

B cell maturation

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About This Item

MDL number:
UNSPSC Code:
51111800

biological source

mouse

recombinant

expressed in NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

potency

0.01-0.03 mg per mL ED50

mol wt

35-40 kDa by SDS-PAGE (reducing)
calculated mol wt 32 kDa

storage condition

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

Biochem/physiol Actions

BCMA, a member of the TNF receptor superfamily, binds to the TNF ligands, APRIL and BAFF. It stimulates the production of IgM in peripheral blood B cells and increases survival of cultured B cells.
Member of the TNF receptor superfamily; binds to the TNF ligands, APRIL and BAFF; stimulates the production of IgM in peripheral blood B cells and increases survival of cultured B cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in 20 mM MES, 50 mM NaCl, pH 6.2.

Analysis Note

The biological activity is measured by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated mouse B cells.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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