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Key Documents

AV51352

Sigma-Aldrich

Anti-PPIA antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-CYPA, Anti-CYPH, Anti-MGC117158, Anti-MGC12404, Anti-MGC23397, Anti-Peptidylprolyl isomerase A (cyclophilin A)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

18 kDa

species reactivity

bovine, mouse, dog, sheep, guinea pig, rat, human, horse, goat

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_066953

UniProt accession no.

P62937

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PPIA(5478)

Immunogen

Synthetic peptide directed towards the middle region of human PPIA

Application

Anti-PPIA antibody produced in rabbit is suitable for western blotting at a concentration of 2.5μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml.

Biochem/physiol Actions

Peptidylprolyl isomerase A (PPIA; CYPA) is a member of peptidyl-prolyl cis-trans isomerase (PPIase) family that is involved in cis-trans isomerization of proline imidic peptide bonds in oligopeptides and acceleration of protein folding.

Sequence

Synthetic peptide located within the following region: TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC17687

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Dong-Rong Yi et al.
Journal of virology, 93(1) (2018-10-20)
Type I interferon (IFN) inhibits viruses by inducing the expression of antiviral proteins. The IFN-induced myxovirus resistance B (MxB) protein has been reported to inhibit a limited number of viruses, including HIV-1 and herpesviruses, but its antiviral coverage remains to
Lauren C McGowan et al.
Biophysical journal, 104(1), 216-226 (2013-01-22)
Enzyme catalysis is central to almost all biochemical processes, speeding up rates of reactions to biological relevant timescales. Enzymes make use of a large ensemble of conformations in recognizing their substrates and stabilizing the transition states, due to the inherent

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