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Key Documents

AV49048

Sigma-Aldrich

Anti-CDYL2 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Chromodomain protein, Y-like 2, Anti-FLJ38866

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100 μL
$541.00

$541.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
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100 μL
$541.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$541.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

56 kDa

species reactivity

guinea pig, human, mouse, bovine, rat, horse, rabbit

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_689555

UniProt accession no.

Q8N8U2

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CDYL2(124359)

Immunogen

Synthetic peptide directed towards the N terminal region of human CDYL2

Application

Anti-CDYL2 antibody produced in rabbit is suitable for western blotting at a concentration of 2.5μg/ml.

Biochem/physiol Actions

Chromodomain protein, Y-like 2 (CDYL2) belongs to the family of chromodomain Y chromosome (CDY) proteins that mediate histone acetylation during spermiogenesis and regulation of transcription corepressors. CDYL2 binds to multiple ARK(S/T) motifs and is present in all mammals.

Sequence

Synthetic peptide located within the following region: NPPLAKPKKGYSGKPSSGGDRATKTVSYRTTPSGLQIMPLKKSQNGMENG

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC20421

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Steve Dorus et al.
Human molecular genetics, 12(14), 1643-1650 (2003-07-03)
Theories predict that the long-term survival of duplicated genes requires their functional diversification, which can be accomplished by either subfunctionalization (the partitioning of ancestral functions among duplicates) or neofunctionalization (the acquisition of novel function). Here, we characterize the CDY-related mammalian
Wolfgang Fischle et al.
The Journal of biological chemistry, 283(28), 19626-19635 (2008-05-03)
Previous studies have shown two homologous chromodomain modules in the HP1 and Polycomb proteins exhibit discriminatory binding to related methyllysine residues (embedded in ARKS motifs) of the histone H3 tail. Methylated ARK(S/T) motifs have recently been identified in other chromatin

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