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Key Documents

AV48293

Sigma-Aldrich

Anti-EIF3M antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-B5, Anti-Eukaryotic translation initiation factor 3, subunit M, Anti-FLJ29030, Anti-GA17, Anti-Hfl-B5, Anti-PCID1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

42 kDa

species reactivity

human, bovine, rabbit, guinea pig, horse, mouse, dog, rat

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_006351

UniProt accession no.

Q7L2H7

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... EIF3M(10480)

General description

EIF3M codes a unit of the eukaryotic translation initiation factor that regulates protein synthesis. Studies have reported that eIF3m expression modulates tumrogenesis genes in human colon cancer.
Rabbit Anti-EIF3M antibody recognizes canine, bovine, zebrafish, human, mouse, rat, and chicken EIF3M.

Immunogen

Synthetic peptide directed towards the N terminal region of human EIF3M

Application

Rabbit Anti-EIF3M antibody is suitable for western blot applications at a concentration of 1μg/ml and for IHC at 4-8μg/ml.

Biochem/physiol Actions

EIF3M is a broadly expressed protein containing putative membrane fusion domains that acts as a receptor or coreceptor for entry of herpes simplex virus (HSV).HFLB5 encodes a broadly expressed protein containing putative membrane fusion domains that acts as a receptor or coreceptor for entry of herpes simplex virus (HSV) (Perez et al., 2005 [PubMed 15919898]).[supplied by OMIM].

Sequence

Synthetic peptide located within the following region: MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACD

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC18633

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S-H Goh et al.
Oncogene, 30(4), 398-409 (2010-09-15)
Abnormal regulation of gene expression is essential for tumorigenesis. Recent studies indicate that regulation of oncogene expression and neoplastic transformation are controlled by subunits of eukaryotic translation initiation factors (eIFs). Here we focused on eIF3 performing a pivotal role in

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