Synthetic peptide directed towards the C terminal region of human MLF2
Application
Anti-MLF2 (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml.
Biochem/physiol Actions
MLF2 gene encodes for myeloid leukemia factor 2, which is a ubiquitously expressed, 248 amino acid containing protein. MLF2 gene locus mapped on human chromosome 12p13. Single nucleotide polymorphisms (SNP) in MLF2 gene serves as a marker for selecting coccidiosis resistance in chickens. Additionally, changes in the MLF2 expression facilitates as novel mechanisms of action of flavonoids at the molecular level.
Sequence
Synthetic peptide located within the following region: WRRETSRFRQQRPLEFRRLESSGAGGRRAEGPPRLAIQGPEDSPSRQSRR
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
The Journal of nutrition, 134(10), 2509-2516 (2004-10-07)
We performed a functional genomic analysis to study the effect of epicatechin and polyphenolic cocoa extract in the human colon adenocarcinoma cell line Caco-2. The specific Human Hematology/Immunology cDNA arrays by Clontech, containing 406 genes in duplicate, were used. The
Associations between the parameters of resistance to coccidiosis and SNP in 3 candidate genes located on chromosome 1 [T cell receptor-beta (TCR-beta), myeloid leukemia factor 2 (MLF2), and lymphotactin] were determined. Single nucleotide polymorphisms were genotyped in 24 F1 generation
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