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Key Documents

AV43618

Sigma-Aldrich

Anti-MTTP antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-ABL, Anti-MGC149819, Anti-MGC149820, Anti-MTP, Anti-Microsomal triglyceride transfer protein

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About This Item

UNSPSC Code:
12352203

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

mol wt

97 kDa

species reactivity

rat, guinea pig, rabbit, mouse, horse, bovine, pig, canine, human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_000244

UniProt accession no.

P55157

storage temp.

−20°C

Gene Information

human ... MTTP(4547)

General description

Microsomal triglyceride transfer protein (MTP), an endoplasmic reticulum chaperone that loads lipids onto apolipoprotein B, resides in the endoplasmic reticulum of hepatocytes. Microsomal triglyceride transfer protein (MTP) and protein disulfide isomerase (PDI) form a transmembrane heterodimeric complex called the microsomal triglyceride transfer protein which transfers phospholipids, triglycerides and cholesterol esters from liver cells into the plasma.

Specificity

Anti-MTTP polyclonal antibody bovine, canine, pig, human, mouse, rat, and chicken microsomal triglyceride transfer proteins.

Immunogen

The immunogen for anti-MTTP antibody: synthetic peptide derected towards the N terminal of human MTTP

Application

Anti-MTTP polyclonal antibody is used to tag microsomal triglyceride transfer protein for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of microsomal triglyceride transfer protein in the transfer of lipids onto apolipoprotein B.

Sequence

Synthetic peptide located within the following region: MILLAVLFLCFISSYSASVKGHTTGLSLNNDRLYKLTYSTEVLLDRGKGK

Physical form

Lyophilized from PBS buffer with 2% sucrose

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC15947

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Lucas Martins França et al.
Oxidative medicine and cellular longevity, 2019, 9417498-9417498 (2019-04-25)
Syzygium cumini is used worldwide for the treatment of metabolic syndrome-associated outcomes. Previously, we described the antihypertriglyceridemic effect of the hydroethanolic extract of S. cumini leaf (HESc) in monosodium L-glutamate- (MSG-) induced obese rats. This study sought to investigate the

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