ZKSCAN4 is a zinc finger protein that has SCAN and KRAB domains. This protein is known to interact with glucocorticoid receptor. Rabbit Anti-ZKSCAN4 antibody recognizes bovine, human, mouse, and rat ZKSCAN4.
Immunogen
Synthetic peptide directed towards the N terminal region of human ZKSCAN4
Application
Rabbit Anti-ZKSCAN4 antibody is suitable for western blot applications at a concentration of 1 μg/ml.
Biochem/physiol Actions
ZNF307 contains 1 SCAN box domain, 1 KRAB domain and 7 C2H2-type zinc fingers. It belongs to the Krueppel C2H2-type zinc-finger protein family and may be involved in transcriptional regulation.
Sequence
Synthetic peptide located within the following region: EVRAPCSPARGPERSRQRFRGFRYPEAAGPREALSRLRELCGQWLQPEMH
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Journal of molecular endocrinology, 42(2), 105-117 (2008-11-15)
To search for proteins interacting with the glucocorticoid receptor, we adapted Aronheim's reverse RAS recruitment system relying on the Saccharomyces cerevisiae mutant cdc25-2, which has a temperature-dependent defect in its RAS signaling pathway driving proliferation. The full-length human glucocorticoid receptor
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