Synthetic peptide directed towards the N terminal region of human POLR2I
Biochem/physiol Actions
POLR2I is a subunit of RNA polymerase II and mediates the formation of DNA binding domain of the enzyme. It regulates the mRNA synthesis in the eukaryotes.
Sequence
Synthetic peptide located within the following region: ACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQ
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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The structure of the gene encoding the 14.5 kDa subunit of the human RNA polymerase II (or B) has been elucidated. The gene consists of six exons, ranging from 52 to over 101 bp, interspaced with five introns ranging from
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