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Key Documents

AV32430

Sigma-Aldrich

Anti-BHLHB5 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Basic helix-loop-helix domain containing, class B, 5

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

37 kDa

species reactivity

mouse, bovine, guinea pig, rat, human, rabbit

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_689627

UniProt accession no.

Q8NFJ8

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BHLHB5(27319)

General description

BHLHB5 is a basic helix-loop-helix transcription factor that is expressed in brain tissues, with its highest expression being in cerebellar cells. BHLHB5 is known to transcriptionally repress human PAX6 promoter.
Rabbit Anti-BHLHB5 antibody recognizes bovine, zebrafish, human, mouse, rat, and chicken BHLHB5.

Immunogen

Synthetic peptide directed towards the N terminal region of human BHLHB5

Application

Rabbit Anti-BHLHB5 antibody is suitable for western blotting at a concentration of 1μg/ml.

Biochem/physiol Actions

BHLHB5 is a member of family of basic helix-loop-helix (bHLH) transcription factors. Members of this family have been implicated in many aspects of neural development, including cell growth, differentiation, and cell migration.

Sequence

Synthetic peptide located within the following region: LPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPR

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC1911

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Zheng-Ping Xu et al.
Genomics, 80(3), 311-318 (2002-09-06)
The genes encoding basic helix-loop-helix (bHLH) transcription factors have been implicated in many aspects of neural development, including cell growth, differentiation, and cell migration. Using both genomic and cDNA mouse and human clones encoding a neural-specific bHLH protein, human BHLHB5

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