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AV31709

Sigma-Aldrich

Anti-FOXD2 antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-Forkhead box D2

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100 μL
$457.00

$457.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
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100 μL
$457.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$457.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

49 kDa

species reactivity

human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_004465

UniProt accession no.

Q5SVZ3

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... FOXD2(2306)

General description

Forkhead/winged helix (FOX) transcription factors regulate cellular metabolism and cell cycle. FOXD2 is known to function as a modulator of R1α1b promoter and has been implicated in T-cell activation.
Rabbit Anti-FOXD2 antibody recognizes human, and mouse FOXD2.

Immunogen

Synthetic peptide directed towards the N terminal region of human FOXD2

Application

Rabbit Anti-FOXD2 antibody can be used for western blot applications at a concentration of 1.25μg/ml.

Biochem/physiol Actions

FOXD2 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined.

Sequence

Synthetic peptide located within the following region: LPARSGPRAPRDVLPHGHEPPAEEAEADLAEDEEESGGCSDGEPRALASR

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC7955

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C Christian Johansson et al.
The Journal of biological chemistry, 278(19), 17573-17579 (2003-03-07)
Forkhead/winged helix (FOX) transcription factors are essential for control of the cell cycle and metabolism. Here, we show that spleens from Mf2-/- (FOXD2-/-) mice have reduced mRNA (50%) and protein (35%) levels of the RIalpha subunit of the cAMP-dependent protein
Hyo-Min Kim et al.
Nucleic acids research, 51(12), 6143-6155 (2023-05-09)
Somatic stem cells contribute to normal tissue homeostasis, and their epigenomic features play an important role in regulating tissue identities or developing disease states. Enhancers are one of the key players controlling chromatin context-specific gene expression in a spatial and

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