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AV01028

Sigma-Aldrich

Anti-GSK3A antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-Glycogen synthase kinase 3 α

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About This Item

UNSPSC Code:
12352203

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

51 kDa

species reactivity

canine, pig, human, rat, bovine, mouse

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... GSK3A(2931)

General description

Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase that is involved in Wnt and PI3K signaling. GSK3A has been implicated in memory dysfunctions and neurodegeneration related to Alzheimer′s disease.
Rabbit Anti-GSK3A antibody recognizes bovine, human, mouse, and rat GSK3A.

Immunogen

Synthetic peptide directed towards the N terminal region of human GSK3A

Application

Rabbit Anti-GSK3A antibody is suitable for use in western blot applications at 1.25μg/ml.

Sequence

Synthetic peptide located within the following region: MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGK

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Karl Peter Giese
IUBMB life, 61(5), 516-521 (2009-04-25)
Abnormalities in molecular signalling have been implicated in neurodegeneration. It is emerging that glycogen synthase kinase-3 (GSK-3) is a key signalling molecule that induces neurodegeneration and deficits in memory formation related to Alzheimer's disease (AD). Early stages of AD are

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