Ataxin-7 is a protein encoded by the spinocerebellar ataxia type 7 (SCA7) gene. Ataxin-7 is known to affect cone-rod homeobox protein (CRX) functions that eventually cause cone-rod dystrophy in mouse models of SCA7. Rabbit Anti-Ataxin-7 antibody recognizes human Ataxin-7.
Immunogen
synthetic peptide corresponding to amino acid residues 1-17 from human ataxin-7. This sequence is completely conserved in mouse ataxin-7.
Application
Rabbit Anti-Ataxin-7 antibody can be used for western blot assays at 1μg/ml.
Physical form
Solution in phosphate buffered saline containing 1.0 mg/mL BSA and 0.05% sodium azide.
Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant disorder caused by a CAG repeat expansion. To determine the mechanism of neurotoxicity, we produced transgenic mice and observed a cone-rod dystrophy. Nuclear inclusions were present, suggesting that the disease pathway
Questions
Reviews
★★★★★ No rating value
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.