A7785
Apolipoprotein C-I from human plasma
≥95% (SDS-PAGE), lyophilized powder
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100 μG
$304.00
About This Item
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biological source
human
Quality Level
assay
≥95% (SDS-PAGE)
form
lyophilized powder
mol wt
average mol wt 6.6 kDa
technique(s)
inhibition assay: suitable
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... APOC1(341)
General description
Very low density lipoprotein.
Application
Apolipoprotein C-1 directly interferes with fatty acid uptake and is a major plasma inhibitor of cholesterol ester transfer protein. Apolipoprotein C-I has been used to develop a quantitative strategy, named secretome-derived isotopic tag (SDIT), to concurrently identify and quantify the adipocyte-secreted plasma proteins from normal and high-fat-diet (HFD) induced obese mice.
Biochem/physiol Actions
Interferes directly with fatty acid uptake and is the major plasma inhibitor of cholesterol ester transfer protein.
Physical form
Lyophilized from 10 mM NH4HCO3, pH 7.5
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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B S Suri et al.
The Biochemical journal, 178(2), 455-466 (1979-02-15)
1. The work reported was designed to provide quantitative information about the capacity of the extrahepatic tissues of the rat to degrade injected VLD lipoproteins (very-low-density lipoproteins, d less than 1.006) to LD lipoproteins (low-density lipoproteins, d 1.006--1.063) and to
Rong-Xia Li et al.
Journal of proteome research, 11(5), 2851-2862 (2012-03-13)
We developed a quantitative strategy, named secretome-derived isotopic tag (SDIT), to concurrently identify and quantify the adipocyte-secreted plasma proteins from normal and high-fat-diet (HFD) induced obese mice, based on the application of isotope-labeled secreted proteins from cultured mouse adipocytes as
Nathan L Meyers et al.
Biochemistry, 51(6), 1238-1248 (2012-01-24)
Apolipoprotein C-I (apoC-I) is an important constituent of high-density lipoprotein (HDL) and is involved in the accumulation of cholesterol ester in nascent HDL via inhibition of cholesterol ester transfer protein and potential activation of lecithin:cholesterol acyltransferase (LCAT). As the smallest
Articles
Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.
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