A Disintegrin And Metalloproteinase-33 (ADAM-3) is a widely expressed protein that regulates cell-attachment by binding to integrins via cysteine-rich domains. ADAM-33 has also been associated with asthma susceptibility. Rabbit Anti-ADAM-33, Cytoplasmic Domain antibody binds to the cytoplasmic end of human ADAM-33.
By immunoblotting against the reduced protein, the antibody identifies bands at 99 kDa (minor band), 58 kDa (major band), and cleaved products in cell lysates.
Immunogen
synthetic peptide corresponding to cytoplasmic domain of human ADAM-33.
Application
Rabbit Anti-ADAM-33, Cytoplasmic Domain antibody can be used for western blot assays at 1:1,000.
Physical form
Solution in phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.
Asthma is a common respiratory disorder characterized by recurrent episodes of coughing, wheezing and breathlessness. Although environmental factors such as allergen exposure are risk factors in the development of asthma, both twin and family studies point to a strong genetic
The ADAM family of membrane-anchored proteins has a unique domain structure, with each containing a disintegrin and metalloprotease (ADAM) domain. We have isolated mouse and human cDNAs encoding a novel member of the ADAM family. The mouse and human predicted
Questions
Reviews
★★★★★ No rating value
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
