ADAMT5 is a member of the family of ADAMTs proteins that contain 3 specific domains: MMP, disintegrin, and a thrombospondin type-1 domain. ADAMT5 is highly expressed in cartilage.
By immunoblotting against the reduced protein, the antibody identifies the zymogen form at 120 kDa, activated form at 73 kDa (major band), and breakdown products at 50 kDa and 40 kDa in cell lysates.
Rabbit Anti-ADAMTS-5, C-terminal antibody binds to the C-terminus of human ADAMTS-5.
Immunogen
synthetic peptide corresponding to the C-terminus of human ADAMTS-5.
Application
Rabbit Anti-ADAMTS-5, C-Terminal antibody can be used for western blot applications at a dilution of 1:1,000.
Physical form
Solution in phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.
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Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.
Osteoarthritis and cartilage, 23(12), 2259-2268 (2015-07-15)
To identify whether cartilage master regulator SRY-related protein 9 (SOX9) mediates A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) dysregulation during osteoarthritis (OA) cartilage degeneration. Twenty-two randomly selected OA patients were evaluated using Outerbridge Classification via arthroscopy. Haematoxylin-eosin (HE), Safranin
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