A5973

Amyloid-β-Protein Fragment 1-40, All D-Amino Acids

>70% (HPLC), lyophilized powder

• Synonym(s): β-Amyloid (Aβ)[1-40, all D-amino acids]
• MDL number: MFCD03454653
• UNSPSC Code: 12352200

Properties

• assay: >70% (HPLC)
• form: lyophilized powder
• mol wt: 4331
• composition: Protein content, ~80%
• solubility: H₂O: soluble
• UniProt accession no.: P05067; P08592; P12023
• storage temp.: −20°C
• Gene Information: human ... APP(351) ; mouse ... APP(11820) ; rat ... APP(54226)

Description

Amino Acid Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val

Application

Used in the study of plaques and tangles that occur in Alzheimer′s disease (AD) patients.

Biochem/physiol Actions

This D-amino acid peptide functions as a control useful in elucidating structural dependence of aggregation properties characteristic of the amyloid-β 1-40 peptide associated with plaque formation and Alzheimer′s disease.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)