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A5626

Sigma-Aldrich

Acetylthiocholine chloride

≥99% (TLC), powder

Synonym(s):

(2-Mercaptoethyl)trimethylammonium chloride acetate

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1 G
$101.00
5 G
$367.00

$101.00

Available to ship onApril 29, 2025Details

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1 G
$101.00
5 G
$367.00

About This Item

Linear Formula:
CH3COSCH2CH2N(CH3)3Cl
CAS Number:
6050-81-3
Molecular Weight:
197.73
EC Number:
227-953-7
MDL number:
MFCD00038727
UNSPSC Code:
12352204
PubChem Substance ID:
24278219
NACRES:
NA.83

$101.00

Available to ship onApril 29, 2025Details

Quality Level

200

assay

≥99% (TLC)

form

powder

solubility

water: 100 mg/mL, clear to slightly hazy, colorless

storage temp.

−20°C

SMILES string

[Cl-].CC(=O)SCC[N+](C)(C)C

InChI

1S/C7H16NOS.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key

GZYVLKKMMDFCKR-UHFFFAOYSA-M

Gene Information

human ... ACHE(43)

Application

Acetylthiocholine chloride has been used to determine the acetylcholine esterase activity of semen exosomes (SE).[1] It has also been used as a substrate for acetylcholine esterase in microcalorimetric study of its kinetic parameters.[2]

Biochem/physiol Actions

Acetylcholinesterase (AChE) enzyme plays an important physiological role in the neurotransmission process.[2]
Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK2494
BCCH1201
BCCG2108
BCCF5118
BCCC1737

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Tanja Botić et al.
European journal of medicinal chemistry, 136, 294-304 (2017-05-16)
The brominated pyrroloiminoquinone alkaloids discorhabdins B, L and G and 3-dihydro-7,8- dehydrodiscorhabdin C, isolated from methanol extracts of two specimens of Latrunculia sp. sponges collected near the Antarctic Peninsula, are here demonstrated for the first time to be reversible competitive
Shalini Nagabooshanam et al.
Scientific reports, 9(1), 19862-19862 (2019-12-29)
An Electrochemical micro Analytical Device (EµAD) was fabricated for sensitive detection of organophosphate pesticide chlorpyrifos in the food chain. Gold microelectrode (µE) modified with Zinc based Metal Organic Framework (MOF-Basolite Z1200) and Acetylcholinesterase (AChE) enzyme served as an excellent electro-analytical
Isolation of Exosomes from Semen for in vitro Uptake and HIV-1 Infection Assays
Madison MN, et al.
Bio-protocol, 7(7) (2017)
Lindon W K Moodie et al.
Organic & biomolecular chemistry, 14(47), 11220-11229 (2016-11-15)
The marine secondary metabolite stryphnusin (1) was isolated from the boreal sponge Stryphnus fortis, collected off the Norwegian coast. Given its resemblance to other natural acetylcholinesterase antagonists, it was evaluated against electric eel acetylcholinesterase and displayed inhibitory activity. A library
Jerneja Kladnik et al.
International journal of molecular sciences, 21(16) (2020-08-13)
The increasing number of Alzheimer's disease (AD) cases requires the development of new improved drug candidates, possessing the ability of more efficient treatment as well as less unwanted side effects. Cholinesterase enzymes are highly associated with the development of AD
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