Adrenergic receptors (ARs) belong to the G protein-coupled receptor superfamily that interacts with epinephrine and norepinephrine. There are nine receptor subtypes which include three α1AR subtypes (α1A/D, α1B, and α1C), three α2ARs (α2A, α2B, and α2C), and three βAR subtypes (β1, β2, and β3). Adrenergic receptors have been implicated in many diseases such as hypertension, glaucoma, cardiac disorders, diabetes, impotence and depression. Rabbit Anti-α1C Adrenergic Receptor antibody specifically recognizes human α1C adrenergic receptor.
Immunogen
synthetic peptide corresponding to the third cytoplasmic loop of human α1C adrenergic receptor. The immunizing peptide has 100% homology with the rat and mouse gene.
Application
Rabbit Anti-α1C Adrenergic Receptor can be used for immunohistochemistry at 2μg/mL using prostate and glandular epithelial tissues.
Cyclin-dependent kinases (CDKs) contribute to vital cellular processes including cell cycle regulation. Loss of CDKs is associated with impaired insulin secretion and β cell survival; however, the function of CDK8 in β cells remains elusive. Here, we report that genetic
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