A4469

Monoclonal Anti-ACTR/AIB1 antibody produced in mouse

clone AX 15, ascites fluid

• MDL number: MFCD02095791
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 200
• conjugate: unconjugated
• antibody form: ascites fluid
• antibody product type: primary antibodies
• clone: AX 15, monoclonal
• mol wt: antigen 150 kDa
• contains: 0.035% sodium azide; 30% glycerol
• species reactivity: human
• technique(s): immunoprecipitation (IP): 15 μL using 500 μg of a BG-1 ovarian cell RIPA lysate.; western blot (chemiluminescent): 1:500 using RIPA lysates of BG-1 ovarian cancer cells
• isotype: IgG
• UniProt accession no.: Q9Y6Q9
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... NCOA3(8202)

Description

General description

ACTR associates with estrogen receptors in breast and ovarian cancers and stimulates transcription. Hence, ACTR has been implicated in the carcinogenesis of breast and ovarian tumors. Mouse monoclonal Anti-ACTR/AIB1 antibody recognizes human ACTR (150kD) and another doublet (110kD) by immunoblotting.

ACTR, a nuclear receptor coactivator, is also referred to as amplified in breast cancer 1 (AIB1), thyroid hormone receptor activator molecule-1 (TRAM-1), receptor-associated coactivator 3 (RAC3 and SRC3).

Immunogen

GST fusion protein containing amino acids 605-1294 of human ACTR.

Application

Mouse monoclonal can be used for immunoprecipitation (15μL using 500μg of a BG-1 ovarian cell RIPA lysate) and western blot (1:500, using RIPA lysates of BG-1 ovarian cancer cells) assays.

Physical form

The product is supplied as mouse ascites fluid, containing 30% glycerol and 0.035% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids