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A4229

Sigma-Aldrich

Anti-A3 Adenosine Receptor antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
MFCD02095794
UNSPSC Code:
12352203

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

availability

not available in Japan

concentration

~1 mg/mL

technique(s)

immunoblotting: suitable using human kidney tissue
immunohistochemistry: suitable using human kidney

UniProt accession no.

P0DMS8

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ADORA3(140)

General description

ADORA3 is a G-protein (Gi-coupled) coupled receptor. ADORA3 has high expression in mast cells ans has been shown to regulate mast cell differentiation.
Rabbit anti-A3 adenosine receptor antibody recognizes A3 adenosine receptor in human kidney tissue by immunohistochemistry.

Immunogen

synthetic peptide corresponding to the second extracellular loop of human adenosine A3 receptor, conjugated to KLH.

Application

Rabbit anti-A3 adenosine receptor antibody can be used for immunofluorescent staining applications. The antibody can also be used for immunohistochemistry assays.

Physical form

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
091M1907
058K1602
028K1393
015K1044

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Azlina A Razak et al.
Diabetes & vascular disease research, 15(6), 528-540 (2018-08-23)
There is clinical and experimental evidence for altered adenosine signalling in the fetoplacental circulation in pregnancies complicated by diabetes, leading to adenosine accumulation in the placenta. However, the consequence for fetoplacental vasocontractility is unclear. This study examined contractility to adenosine
F von Versen-Höynck et al.
Placenta, 30(5), 434-442 (2009-03-24)
Placental hypoxia as a result of impaired trophoblast invasion is suggested to be involved in the pathophysiology of preeclampsia. Hypoxia is a potent stimulus for the release of adenosine, and the actions of adenosine are mediated through four adenosine receptors

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