A3851

Anti-ADAM-15, Cytoplasmic Domain antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

• Synonym(s): Anti-A Disintegrin And Metalloproteinase-15, Anti-MDC15, Anti-Metargidin
• MDL number: MFCD03702124
• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous glycerol solution
• species reactivity: human
• concentration: ~1 mg/mL
• technique(s): western blot: 1:1,000
• UniProt accession no.: Q13444
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ADAM15(8751)

Description

General description

ADAM-15 (MDC-15, metargidin) is a membrane-anchored disintegrin and metalloprotease that is present on the cell surface. ADAM-15 may play a role in cell-cell interactions through its association with integrins. Studies have reported that ADAM15 is involved in the migration of mesangial cells.
Rabbit anti-ADAM-15, cytoplasmic domain antibody localizes human ADAM15. By immunoblotting against the reduced protein, the antibody recognizes bands of 110kDa (zymogen) and 90kDa (furin-processed form) of ADAM15. A series of cleaved products at 55kDa and 40kDa can also be seen in reduced immunoblots of cell lysates.

Immunogen

synthetic peptide corresponding to the cytoplasmic domain of human ADAM-15.

Application

Rabbit anti-ADAM-15, cytoplasmic domain antibody can be used for western blot applications at 1:1,000.

Physical form

Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.