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About This Item
Linear Formula:
C17H18FN3O3C3H6O3
Molecular Weight:
421.42
UNSPSC Code:
51101500
NACRES:
NA.85
Recommended Products
assay
≥98% (HPLC)
form
solid
color
white to faint yellow
solubility
DMSO: 1.5 mg/mL
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mode of action
DNA synthesis | interferes
enzyme | inhibits
storage temp.
−20°C
Application
Ciprofloxacin lactate was used as standard in Rayleigh scattering technique to determine the amount of the antibiotic in various drugs.[1]
Biochem/physiol Actions
Ciproflaxacin is a fluoroquinolone and a broad-spectrum activity against Gram-positive and Gram-negative bacteria. The mode of action of ciprofloxacin involves the inhibition DNA gyrase and subsequent inhibition of replication by tight DNA binding. Pathogens resistant to multiple antibiotics have been found to be susceptible to Ciproflaxacin.[2][3]
Packaging
100mg,1g
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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M LeBel
Pharmacotherapy, 8(1), 3-33 (1988-01-01)
Ciprofloxacin, considered a benchmark when comparing new fluoroquinolones, shares with these agents a common mechanism of action: inhibition of DNA gyrase. While ciprofloxacin demonstrated a fairly good activity against gram-positive bacteria, it is against gram-negative organisms that it proved to
Rapid determination of ciprofloxacin lactate in drugs by the Rayleigh light scattering technique
Measurement Science and Technology, 18, 859-859 (2007)
Prabodh Chander Sharma et al.
Journal of enzyme inhibition and medicinal chemistry, 25(4), 577-589 (2010-03-20)
In the current practices of anti-infective therapy, ciprofloxacin is a very popular fluoroquinolone having a broad spectrum of activity and diverse therapeutic prospects. The reasons for its wide use include multiresistant pathogens susceptible only to ciprofloxacin. The available clinical evidence
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