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A2431

Sigma-Aldrich

N6-(4-Aminobenzyl)adenosine–Agarose

aqueous glycerol suspension

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About This Item

MDL number:
UNSPSC Code:
23151817
NACRES:
NA.56

form

aqueous glycerol suspension

Quality Level

extent of labeling

10-20 μmol per mL

matrix

cross-linked 4% beaded agarose

matrix attachment

amino

matrix spacer

8 atoms

storage temp.

2-8°C

Application

N6-(4-Aminobenzyl)adenosine is an agarose used in affinity chromatography, protein chromatography and in nucleotide/coenzyme resins and is particularly useful for the purification of A2-adenosine receptors.

Physical form

Suspension in 50% glycerol and 0.02% thimerosal

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Z Gao et al.
The Biochemical journal, 338 ( Pt 3), 729-736 (1999-03-03)
We examined the effects of exposing A1 adenosine receptors (A1ARs) to an agonist on the stability and phosphorylation state of receptor-guanine nucleotide-binding regulatory protein (R-G-protein) complexes. Non-denatured recombinant human A1ARs extended on the N-terminus with hexahistidine (His6) and the FLAG
R Munshi et al.
The Journal of biological chemistry, 264(25), 14853-14859 (1989-09-05)
A1 adenosine receptors and guanine nucleotide-binding proteins (G proteins) solubilized with 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate have been co-purified from bovine cerebral cortex. A portion of solubilized receptors which displays high affinity GTP-sensitive agonist binding (40-50%) adheres tightly to agonist affinity columns composed of
5'-S-(2-aminoethyl)-N6-(4-nitrobenzyl)-5'-thioadenosine (SAENTA), a novel ligand with high affinity for polypeptides associated with nucleoside transport. Partial purification of the nitrobenzylthioinosine-binding protein of pig erythrocytes by affinity chromatography
Agbanyo, F.R., et al.
The Biochemical Journal, 270, 604-614 (1990)

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