A212000

DMT-2′O-TBDMS-rA(tac) Phosphoramidite

• Synonym(s): DMT-2′O-TBDMS-rA(tac) amidite, N-[[4-(1,1-dimethylethyl)phenoxy]acetyl]-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-adenosine, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
• Empirical Formula (Hill Notation): C₅₈H₇₆N₇O₉PSi
• CAS Number: 149989-64-0
• Molecular Weight: 1074.32
• MDL number: MFCD09842118
• UNSPSC Code: 41116105
• PubChem Substance ID: 329770760

Properties

• product line: Proligo Reagents
• assay: ≥98% (³¹P-NMR); ≥98.0% (reversed phase HPLC)
• form: solid
• technique(s): oligo synthesis: suitable
• λ: conforms (UV/VIS Identity)
• nucleoside profile: base: adenosine; base protecting group: TAC; 2' protecting group: TBDMS; 5' protecting group: DMT; deprotection: standard
• storage temp.: −20°C
• SMILES string: COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)COc5ccc(cc5)C(C)(C)C)ncnc34)(c6ccccc6)c7ccc(OC)cc7
• InChI: 1S/C58H76N7O9PSi/c1-39(2)65(40(3)4)75(71-34-18-33-59)73-51-48(35-70-58(42-19-16-15-17-20-42,43-23-27-45(67-11)28-24-43)44-25-29-46(68-12)30-26-44)72-55(52(51)74-76(13,14)57(8,9)10)64-38-62-50-53(60-37-61-54(50)64)63-49(66)36-69-47-31-21-41(22-32-47)56(5,6)7/h15-17,19-32,37-40,48,51-52,55H,18,34-36H2,1-14H3,(H,60,61,63,66)/t48-,51-,52-,55-,75?/m1/s1
• InChI key: FWMHZIXOXNRHDJ-MGFFOSEMSA-N

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable