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A1900

Sigma-Aldrich

Albumin, Monomer bovine

Monomer ≥97 %

Synonym(s):

Albumin powder, Bovine albumins

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250 MG
$244.00
1 G
$688.80

About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352202
eCl@ss:
42010201
NACRES:
NA.26

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biological source

bovine

Quality Level

assay

≥97% (PAGE)

form

lyophilized powder

composition

Monomer, ≥97%

technique(s)

SDS-PAGE: suitable

solubility

H2O: soluble 50 mg/mL

UniProt accession no.

storage temp.

2-8°C

Gene Information

bovine ... ALB(280717)

General description

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands. [1]

application

Albumin, Monomer bovine has been used as a:
  • molecular weight (MW) and polydispersion index (PDI) reference standard for the analysis of hyaluronic acid (HA)-based eye drops[2]
  • standard in multi-angle light scattering coupled with size exclusion chromatography (SEC-MALS) for calibration[3]
  • model protein to generate subvisible particles (SVPs) for flow imaging microscopy studies[4]

The binding properties of albumin can be used for a wide range of clinical, pharmaceutical, and biochemical applications.[1]

Biochem/physiol Actions

Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.[1]

Preparation Note

Isolated from albumin (A4503) as described for mercaptalbumin in Janatova, J., et al., J. Biol. Chem., 243, 3612 (1968).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Ming-Yuan Su et al.
Nature communications, 8(1), 1516-1516 (2017-11-16)
Peptidoglycan (PG) is a highly cross-linked, protective mesh-like sacculus that surrounds the bacterial cytoplasmic membrane. Expansion of PG is tightly coupled to growth of a bacterial cell and requires hydrolases to cleave the cross-links for insertion of nascent PG material.
John P O'Donnell et al.
Methods in molecular biology (Clifton, N.J.), 2159, 93-113 (2020-06-13)
A common feature of dynamin-related proteins (DRPs) is their use of guanosine triphosphate (GTP) to control protein dynamics. In the case of the endoplasmic- reticulum- (ER)-resident membrane protein atlastin (ATL), GTP binding and hydrolysis result in membrane fusion of ER
Sarita Aryal et al.
Biomolecules, 10(9) (2020-08-30)
In Trichomonas vaginalis (T. vaginalis), cyclophilins play a vital role in dislodging Myb proteins from the membrane compartment and leading them to nuclear translocation. We previously reported that TvCyP1 cyclophilin from T. vaginalis forms a dimer and plays an essential
Pasquale Aragona et al.
Translational vision science & technology, 8(6), 2-2 (2019-11-07)
To assess the physicochemical properties of hyaluronic acid (HA)-based artificial tears. The average molecular weight (MW) and polydispersion index (PDI) of HA in 18 commercially available artificial tears were determined by light scattering/high-performance liquid chromatography. Osmolality, pH, viscosity, and sodium
Manuel Maestre-Reyna et al.
IUBMB life, 73(2), 418-431 (2020-12-30)
Vibrio cholerae is the causative agent of the diarrheal disease cholera, for which biofilm communities are considered to be environmental reservoirs. In endemic regions, and after algal blooms, which may result from phosphate enrichment following agricultural runoff, the bacterium is

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