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92416

Sigma-Aldrich

D-Mannitol 1-phosphate lithium salt

≥95% (TLC)

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10 MG
$715.00

About This Item

Empirical Formula (Hill Notation):
C6H15O9P · xLi+
CAS Number:
Molecular Weight:
262.15 (free acid basis)
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

$715.00


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Quality Level

assay

≥95% (TLC)

form

powder

color

white

storage temp.

−20°C

SMILES string

[P](=O)(OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)(O)O

InChI

1S/C6H15O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h3-11H,1-2H2,(H2,12,13,14)/t3-,4-,5-,6-/m1/s1

InChI key

GACTWZZMVMUKNG-KVTDHHQDSA-N

Application

Mannitol-1-P can be used to detect the transphosphorylation activity of D-mannitol-specific enzyme II expreβed in spheroplasts. [1]

Biochem/physiol Actions

D-Mannitol 1-phosphate is an intermediate in the fructose and mannose metabolism. It takes part in the phosphoenolpyruvate-dependent PEP group translocation (phosphotransferase system or PTS), a major mechanism used by bacteria for carbohydrate uptake.[2]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Enzymes II of the phosphoenolpyruvate-dependent sugar transport systems: a review of their structure and mechanism of sugar transport.
G T Robillard et al.
Biochimica et biophysica acta, 947(3), 493-519 (1988-10-11)
H Rosenberg et al.
Journal of bacteriology, 158(1), 63-68 (1984-04-01)
The phosphate moiety of D-mannitol-1-phosphate in Escherichia coli is subject to rapid turnover and is in close equilibrium with Pi and the phosphorus of fructose-1,6-bisphosphate. These three compounds account for the bulk of 32P label found in cells after several
F F Roossien et al.
Biochemistry, 23(21), 4934-4939 (1984-10-09)
Purified mannitol-specific enzyme II (EIImtl), in the presence of the detergent Lubrol, catalyzes the phosphorylation of mannitol from P-HPr via a classical ping-pong mechanism involving the participation of a phosphorylated EIImtl intermediate. This intermediate has been demonstrated by using radioactive
T Chase
The Biochemical journal, 239(2), 435-443 (1986-10-15)
Mannitol-1-phosphate dehydrogenase was purified to homogeneity, and some chemical and physical properties were examined. The isoelectric point is 4.19. Amino acid analysis and polyacrylamide-gel electrophoresis in presence of SDS indicate a subunit Mr of about 22,000, whereas gel filtration and
Stefan Krahulec et al.
Carbohydrate research, 343(9), 1414-1423 (2008-05-03)
A putative long-chain mannitol-1-phosphate 5-dehydrogenase from Aspergillus fumigatus (AfM1PDH) was overexpressed in Escherichia coli to a level of about 50% of total intracellular protein. The purified recombinant protein was a approximately 40-kDa monomer in solution and displayed the predicted enzymatic

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