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88535

Sigma-Aldrich

Thiocarbohydrazide

purum p.a., suitable for electron microscopy, ≥99.0% (N)

Synonym(s):

Thiocarbonyldihydrazide

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About This Item

Linear Formula:
(NH2NH)2CS
CAS Number:
Molecular Weight:
106.15
Beilstein/REAXYS Number:
506657
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

grade

purum p.a.

assay

≥99.0% (N)

form

crystals

technique(s)

electron microscopy: suitable

mp

171-174 °C (dec.) (lit.)

SMILES string

NNC(=S)NN

InChI

1S/CH6N4S/c2-4-1(6)5-3/h2-3H2,(H2,4,5,6)

InChI key

LJTFFORYSFGNCT-UHFFFAOYSA-N

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Application

Thiocarbohydrazide is used in silver proteinate specific and OTO-method (osmium-thiocarbohydrazide-osmium) methods for staining carbohydrates in electron microscopy. Thiocarbohydrazide may be used in the organic synthesis of metal ion coordinating compounds.

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Danger

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Amit Kumar Sharma et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 78(1), 337-342 (2010-11-26)
2,6-diacetyl pyridine based ligand was synthesized by the reaction of 2,6-diacetyl pyridine with thiocarbohydrazide in presence of acetic acid. The coordination compounds with Cr(III) and Ni(II) metal ions having [Cr(L)X]X2 and [Ni(L)X]X compositions (where L=ligand and X=NO3-, Cl- and CH3COO-)
E A Dunnebier et al.
Hearing research, 90(1-2), 139-148 (1995-10-01)
The stereociliar structures of the guinea-pig cochlear organ of Corti were studied at low-voltage (1-5 kV) with field-emission scanning electron microscope (SEM) using various pre- and post-fixation methods, such as OTOTO (OsO4/thiocrbohydrazide/OsO4/thiocarbohydrazide/OsO4) and TAO (tannic acid/arginine/OsO4), and different dissection procedures
M A Badawy et al.
Archiv der Pharmazie, 324(6), 349-351 (1991-06-01)
Heterocycles containing the indole ring system include some novel pharmacologically active compounds. Isatin and its N-acetylisatin are extremely versatile intermediates in the construction of a variety of heterocyclic systems when reacted with thiosemicarbazide derivatives. Literature survey revealed various interesting reactions
D B Wilson et al.
The Anatomical record, 228(4), 431-436 (1990-12-01)
Functional differentiation of the notochord in rhesus monkey embryos at stages 11-12 (25-28 days of gestation) was analyzed by means of ultrastructural cytochemistry. The notochordal cells exhibited well developed Golgi complexes, rough endoplasmic reticulum, mitochondria, and numerous coated vesicles. Large
D H Yang et al.
The Histochemical journal, 28(1), 33-43 (1996-01-01)
The ontogeny of sulphated glycoconjugate-producing cells in the rat fundic gland has been studied using high iron diamine (HID), Alcian Blue (AB) at pH 1.0, high iron diamine in combination with Alcian Blue at pH 2.5 (HID-AB), cationic colloidal gold

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