68226

Iris 7-WS NHS ester

• Synonym(s): 2-{2-{2-{4-[4-(2,5-Dioxopyrrolidinyloxycarbonyl)butyrylamino]phenoxy}-3-{2-[1-(hex-5-ynyl)-1,3-dihydro-3,3-dimethyl-5-sulfoindol-2-ylidene]ethylidene}cyclohex-1-enyl}vinyl}-1-(hex-5-ynyl)-3,3-dimethyl-3H-indolium-5-sulfonate monopotassium salt
• Empirical Formula (Hill Notation): C₅₇H₆₁KN₄O₁₂S₂
• Molecular Weight: 1097.34
• MDL number: MFCD18452831
• UNSPSC Code: 12352202
• PubChem Substance ID: 329760778

Properties

• fluorescence: λ_ex 777 nm; λ_em 796 nm in 0.1 M phosphate pH 7.0
• storage temp.: −20°C
• SMILES string: [K+].CC1(C)/C(=C\C=C2/CCCC(\C=C\C3=[N+](CCCCC#C)c4ccc(cc4C3(C)C)S([O-])(=O)=O)=C2Oc5ccc(NC(=O)CCCC(=O)ON6C(=O)CCC6=O)cc5)N(CCCCC#C)c7ccc(cc17)S([O-])(=O)=O
• InChI: 1S/C57H62N4O12S2.K/c1-7-9-11-13-35-59-47-29-27-43(74(66,67)68)37-45(47)56(3,4)49(59)31-21-39-17-15-18-40(22-32-50-57(5,6)46-38-44(75(69,70)71)28-30-48(46)60(50)36-14-12-10-8-2)55(39)72-42-25-23-41(24-26-42)58-51(62)19-16-20-54(65)73-61-52(63)33-34-53(61)64;/h1-2,21-32,37-38H,9-20,33-36H2,3-6H3,(H2-,58,62,66,67,68,69,70,71);/q;+1/p-1
• InChI key: SWDBNKZTXOZKMG-UHFFFAOYSA-M

Description

Application

Iris 7-WS NHS ester is used to attach the near-infrared fluorescent dye (NIR) Iris 7-WS to amine containing biomolecules such as proteins, amino acids, and polyamines.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Principle

The NHS group conjugates to amino groups under mild condition and enables convenient labeling of proteins, antibodies, and other amine-containing biomolecules.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable