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60399

Sigma-Aldrich

Potassium iodide

BioUltra, ≥99.5% (AT)

Synonym(s):

KI

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About This Item

Linear Formula:
KI
CAS Number:
7681-11-0
Molecular Weight:
166.00
EC Number:
231-659-4
MDL number:
MFCD00011405
UNSPSC Code:
12352302
PubChem Substance ID:
57651758
NACRES:
NA.25

vapor pressure

1 mmHg ( 745 °C)

product line

BioUltra

assay

≥99.5% (AT)

form

solid

impurities

insoluble matter, passes filter test
≤0.001% total nitrogen (N)

loss

≤0.5% loss on drying, 110 °C

pH

6.0-9.0 (25 °C, 1 M in H2O)

mp

681 °C (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

bromide, chloride (as Cl-): ≤100 mg/kg
iodate (IO3-): ≤2 mg/kg
phosphate (PO43-): ≤10 mg/kg
sulfate (SO42-): ≤10 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤300 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

absorption

cut-off at 273 nm in H2O at 1 M

application(s)

vitamins, nutraceuticals, and natural products

SMILES string

[K+].[I-]

InChI

1S/HI.K/h1H;/q;+1/p-1

InChI key

NLKNQRATVPKPDG-UHFFFAOYSA-M

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Application

Potassium iodide has been used:
  • to inhibit active oxygen as a component of processes such as DNA damage
  • as a chaotropic agent which, in high concentrations can dissolve a gel matrix
  • in the recovery of DNA from gel slices by gel dissolution

Biochem/physiol Actions

Potassium iodide (KI) consists of halogen iodine and the alkali metal potassium. It is used in the form of iodized salt to treat endemic goiter. KI is also used to treat hyperthyroidism and radiation protection of the thyroid gland. KI is useful for the preoperative preparation of patients with Grave′s disease. It also finds its use in treating dermatological conditions like cutaneous sporotrichosis and various inflammatory dermatoses. KI is commonly used as an expectorant. It inhibits the capacity of neutrophils to produce e toxic oxygen intermediates hydrogen peroxide and hydroxyl radicals in vitro.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H372

Hazard Classifications

STOT RE 1 Oral

target_organs

Thyroid

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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H.O. Smith
Methods in Enzymology, 65, 375-375 (1980)
Isolation of large molecular weight DNA from agarose gels for further digestion by restriction enzymes.
N Blin et al.
FEBS letters, 53(1), 84-86 (1975-04-15)
Higson, S.P.J. et al.
Electroanalysis, 6, 431-431 (1994)
S C Clement et al.
Pediatric blood & cancer, 60(11), 1833-1838 (2013-07-09)
Thyroid dysfunction has been reported in up to 52% of patients 1.4 years after treatment with (131) I-Metaiodobenzylguanidine (MIBG) in children with neuroblastoma (NBL), despite the use of potassium-iodide (KI). Our aim was to investigate if the incidence and severity
J B Sterling et al.
Journal of the American Academy of Dermatology, 43(4), 691-697 (2000-09-27)
Potassium iodide (KI) is a useful drug in the dermatologic armamentarium. It is successfully used for inflammatory dermatoses, most notably erythema nodosum, subacute nodular migratory panniculitis, nodular vasculitis, erythema multiforme, and Sweet's syndrome. KI is also successfully used for cutaneous
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