59829
Atto 594 iodoacetamide
BioReagent, suitable for fluorescence
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About This Item
UNSPSC Code:
12352200
product line
BioReagent
assay
≥90% (HPLC)
≥90% (degree of coupling)
form
solid
manufacturer/tradename
ATTO-TEC GmbH
λ
in ethanol (with 0.1% trifluoroacetic acid)
UV absorption
λ: 597-603 nm Amax
suitability
suitable for fluorescence
storage temp.
−20°C
Application
Atto 594 is a novel fluorescent label belonging to the class of Rhodamine dyes. The dye is designed for application in the area of life science, e.g. labeling of DNA, RNA or proteins. Characteristic features of the label are strong absorption, high fluorescence quantum yield, high thermal and photo-stability, excellent water solubility, and very little triplet formation. After coupling to a substrate Atto 594 carries a net electrical charge of -1.
The iodoacetamide derivative reacts, like the maleimide, with a sulfhydryl group forming a thioether bond. It is predominantly used for tagging cystein residues of proteins.
The iodoacetamide derivative reacts, like the maleimide, with a sulfhydryl group forming a thioether bond. It is predominantly used for tagging cystein residues of proteins.
Legal Information
This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Massa J Shoura et al.
Nucleic acids research, 40(15), 7452-7464 (2012-05-17)
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Michael R Williams et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(27), 9228-9237 (2012-07-06)
The potassium channel Kv1.2 α-subunit is expressed in cerebellar Purkinje cell (PC) dendrites where its pharmacological inhibition increases excitability (Khavandgar et al., 2005). Kv1.2 is also expressed in cerebellar basket cell (BC) axon terminals (Sheng et al., 1994), where its
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