Skip to Content
MilliporeSigma
All Photos(1)

Documents

55345

Sigma-Aldrich

N-Methyl-L-threonine

≥98% (TLC)

Synonym(s):

(2S,3R)-3-Hydroxy-2-(methylamino)butyric acid, N-Me-Thr-OH

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C5H11NO3
CAS Number:
2812-28-4
Molecular Weight:
133.15
Beilstein/REAXYS Number:
1722279
MDL number:
MFCD02094308
UNSPSC Code:
12352202
PubChem Substance ID:
329757944

assay

≥98% (TLC)

form

powder

optical activity

[α]/D -24.0±1.0°, c = 1 in 1 M HCl

composition

carbon, 44.2-46.0%
nitrogen, 10.3-10.8%

color

white

storage temp.

2-8°C

SMILES string

CN[C@@H]([C@@H](C)O)C(O)=O

InChI

1S/C5H11NO3/c1-3(7)4(6-2)5(8)9/h3-4,6-7H,1-2H3,(H,8,9)/t3-,4+/m1/s1

InChI key

CCAIIPMIAFGKSI-DMTCNVIQSA-N

Biochem/physiol Actions

N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

D J Gordon et al.
Biochemistry, 40(28), 8237-8245 (2001-07-11)
A potential goal in the prevention or therapy of Alzheimer's disease is to decrease or eliminate neuritic plaques composed of fibrillar beta-amyloid (Abeta). In this paper we describe N-methyl amino acid containing congeners of the hydrophobic "core domain" of Abeta

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service