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Sigma-Aldrich

Bovine Collagen

Bornstein and Traub Type V, 0.25 mg/mL

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.75

biological source

bovine placenta

sterility

sterile

assay

>95% (SDS-PAGE)

form

solution

packaging

vial of 0.5 mg

concentration

0.25 mg/mL

technique(s)

cell culture | mammalian: suitable

solubility

water: miscible

shipped in

wet ice

storage temp.

2-8°C

General description

Collagen is a major component of several human tissues, mainly of bone.[1] Bovine collagen is biodegradable[2] and was first obtained from a fresh calf skin.[3]
Type V Collagen provides structure and strength to connective tissue and is found in many places in the body, especially skin, lung, intestinal walls and walls of blood vessels. This Type V Collagen product is isolated from placenta and is purified using a multi-step process with a final purity of >95%. Type V collagen forms a triple helix composed of a Alpha 1(V)2 Alpha 2(V) heterotrimer.

Type V Collagen is typically used as a thin coating on tissue culture surfaces. This product is generally used in vitro as a substrate scaffold to enhance cell attachment, adherence and proliferation. Type V collagen may be used to culture a variety of cell types.

Biochem/physiol Actions

Collagen acts as a powerful marker for regeneration.[1] Bovine collagen injections are not advisable to individuals undergoing a treatment with steroids.[3] It is used in the deletion of telopeptide allogenic units.[3]

Preparation Note

The product is supplied as a sterile solution at 0.5 mg per vial at approximately 0.15 to 0.30 mg/ml in 100 mM acetic acid.

Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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