Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

45198

Sigma-Aldrich

Enterodiol

≥95.0% (HPLC)

Synonym(s):

3,3′-[2,3-Bis(hydroxymethyl)butane-1,4-diyl]diphenol

Sign Into View Organizational & Contract Pricing

Select a Size

5 MG
$168.00

$168.00


Available to ship onMay 01, 2025Details


Request a Bulk Order

Select a Size

Change View
5 MG
$168.00

About This Item

Empirical Formula (Hill Notation):
C18H22O4
CAS Number:
Molecular Weight:
302.36
Beilstein/REAXYS Number:
8997364
MDL number:
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
form:
solid
assay:
≥95.0% (HPLC)

$168.00


Available to ship onMay 01, 2025Details


Request a Bulk Order

assay

≥95.0% (HPLC)

form

solid

storage temp.

2-8°C

SMILES string

OCC(Cc1cccc(O)c1)C(CO)Cc2cccc(O)c2

InChI

1S/C18H22O4/c19-11-15(7-13-3-1-5-17(21)9-13)16(12-20)8-14-4-2-6-18(22)10-14/h1-6,9-10,15-16,19-22H,7-8,11-12H2

InChI key

DWONJCNDULPHLV-UHFFFAOYSA-N

Application


  • The Development and Evaluation of a Literature-Based Dietary Index for Gut Microbiota.: This study assesses the potential role of enterodiol in shaping gut microbiota, proposing a dietary index that could influence microbial diversity and activity. This research could lead to targeted dietary recommendations for enhancing gut health (Kase et al., 2024).

  • Roles of gender and smoking in the associations between urinary phytoestrogens and asthma/wheeze and lung function.: This analysis includes enterodiol among the phytoestrogens evaluated for their impact on respiratory health, revealing significant insights into how lifestyle factors modulate these effects (Zhang et al., 2024).

  • Obesity-associated inflammatory macrophage polarization is inhibited by capsaicin and phytolignans.: Investigates the efficacy of enterodiol and other phytolignans in modulating inflammatory processes in obesity, offering a potential pathway to mitigate obesity-related inflammation (Poynter et al., 2024).

  • The Perfect Cup, Coffee-Derived Polyphenols and Their Roles in Mitigating Factors Affecting Type 2 Diabetes Pathogenesis.: Highlights research on coffee-derived polyphenols, including enterodiol, exploring their therapeutic potentials in managing and preventing type 2 diabetes (Chapple et al., 2024).

  • Microbial Phenolic Metabolites Are Associated with Improved Cognitive Health.: Discusses how enterodiol, as a microbial metabolite from dietary phenolics, is linked to enhanced cognitive functions, stressing the importance of diet in mental health (Domínguez-López et al., 2024).


Biochem/physiol Actions

Referred to as a "mammalian lignan," enterodiol is produced by metabolism of plant lignans by intestinal flora.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Daniel Hinojosa-Nogueira et al.
Journal of agricultural and food chemistry, 65(20), 4216-4222 (2017-05-06)
Polyphenols are bioactive substances of vegetal origin with a significant impact on human health. The assessment of polyphenol intake and excretion is therefore important. The Folin-Ciocalteu (F-C) method is the reference assay to measure polyphenols in foods as well as
Susana Alejandra Palma-Duran et al.
International journal of food sciences and nutrition, 66(7), 819-825 (2015-09-30)
Phytoestrogens have generated interest in human health in view of their potential effect to reduce the risk of developing chronic diseases. Serum levels of phytoestrogens have been proposed as an alternative to measure the exposure of phytoestrogens. We evaluated the
Shelby L Johnson et al.
Metabolites, 9(4) (2019-04-24)
Increasing evidence supports the beneficial effects of polyphenol-rich diets, including the traditional Mediterranean diet, for the management of cardiovascular disease, obesity and neurodegenerative diseases. However, a common concern when discussing the protective effects of polyphenol-rich diets against diseases is whether
Qi Sun et al.
The American journal of clinical nutrition, 105(1), 159-168 (2017-01-05)
Limited knowledge regarding the reproducibility of biomarkers in 24-h urine samples has hindered the collection and use of the samples in epidemiologic studies. We aimed to evaluate the reproducibility of various markers in repeat 24-h urine samples. We calculated intraclass
Mingyue Zhang et al.
International journal of environmental research and public health, 12(12), 15110-15117 (2015-12-04)
Exposure to artificial or natural endocrine disruptors, such as bisphenol A (BPA) and phytoestrogens has been demonstrated to have health effects, especially in children. Biomonitoring of BPA and phytoestrogens in human urine can be used to assess the intake levels

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service