410R-1

Cytokeratin 10 (EP97) Rabbit Monoclonal Primary Antibody

• UNSPSC Code: 12352202
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP97, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (410R-14); vial of 0.5 mL concentrate (410R-15); bottle of 1.0 mL predilute (410R-17); vial of 1.0 mL concentrate (410R-16); bottle of 7.0 mL predilute (410R-18)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
• isotype: IgG
• control: squamous cell carcinoma
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: cytoplasmic
• Gene Information: human ... KRT10(3858)

Description

General description

Cytokeratin 10 (CK10) belongs to type I and acidic keratin family. It is low molecular weight keratin that is usually expressed in suprabasal keratinocytes and can also be seen in suprabasal cells of internal noncornifying, stratified squamous epithelia.In addition, CK10 is reported to be a typical component of cells of eccrine sweat gland ducts and sebaceous cells.Anti-CK10 is helpful in the identification of well differentiated squamous cell carcinoma derived from skin or from internal organs.However, CK10 was found to be sparse in poorly differentiated squamous cell carcinoma, even though it has been reported that focal CK10 expression has been found in 50% of cases of oral and pharyngeal squamous cell carcinoma.Anti-CK10 has demonstrated utility in the differentiation of extra-mammary Paget′s disease (negative) from basal cell carcinoma and squamous cell carcinoma (positive).

Quality

IVD

IVD

IVD

RUO

Linkage

Cytokeratin 10 Positive Control Slides, Product No. 410S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany