IgG as found on instructions for use or IFU
356R-1
Cytokeratin 5 & 6 (EP24 & EP67) Rabbit Monoclonal Primary Antibody
Synonym(s):
CK 5/6, cytokeratin 5/6
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1 ML
$104.00
1 ML
$104.00
0.1 ML
$127.00
0.1 ML
$127.00
7 ML
$389.00
7 ML
$389.00
0.5 ML
$419.00
0.5 ML
$419.00
1 ML
$591.00
1 ML
$591.00
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1 ML
$104.00
1 ML
$104.00
0.1 ML
$127.00
0.1 ML
$127.00
7 ML
$389.00
7 ML
$389.00
0.5 ML
$419.00
0.5 ML
$419.00
1 ML
$591.00
1 ML
$591.00
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
EP24 & EP67, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (356R-14)
vial of 0.1 mL concentrate Research Use Only (356R-14-RUO)
vial of 0.5 mL concentrate (356R-15)
vial of 1.0 mL concentrate (356R-16)
vial of 1.0 mL concentrate Research Use Only (356R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (356R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (356R-17)
vial of 7.0 mL pre-dilute ready-to-use (356R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (356R-18-RUO)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
control
mesothelioma, prostate, squamous cell carcinoma ((lung))
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... KRT5(3852)
Related Categories
General description
Twenty identified cytokeratins make up a complex family of intermediate filaments.1 Cytokeratin 5 (58kDa) & cytokeratin 6 (56kDa) are type II high molecular weight keratins that are expressed in a broad range of normal tissues including breast, prostate, mesothelium, skin and esophagus.1-3 Anti-Cytokeratin 5 & 6 is a useful immunohistochemical marker in the identification of mesothelioma and lung squamous cell carcinoma.1
Quality
United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO
Canada - IVD
European Union - IVD
Japan - RUO
Linkage
Cytokeratin 5 & 6 Positive Control Slides, Product No. 356S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris buffer, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide
Preparation Note
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Note: This requires a keycode which can be found on your packaging or product label.
Download the latest released IFU
Note: This IFU may not apply to your specific product lot.
Other Notes
For Technical Service please contact: 800-665-7284 or email: [email protected]
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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R Lersch et al.
Molecular and cellular biology, 9(9), 3685-3697 (1989-09-01)
The mitotically active basal layers of most stratified squamous epithelia express 10 to 30% of their total protein as keratin. The two keratins specifically expressed in these cells are the type II keratin K5 (58 kilodaltons) and its corresponding partner
K Takahashi et al.
The Journal of biological chemistry, 270(31), 18581-18592 (1995-08-04)
The human type II keratin 6 (K6; 56 kDa) is expressed in a heterogeneous array of epithelial tissues under normal conditions, but is better known for its strong induction in stratified epithelia that feature an enhanced cell proliferation rate or
Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas.
Ordo?ez, N.G.
Modern Pathology, 15, 6-10 (2002)
N G Ordóñez
The American journal of surgical pathology, 22(10), 1215-1221 (1998-10-20)
The immunohistochemical diagnosis of mesothelioma is commonly made by using a battery of antibodies that reacts with lung adenocarcinomas but not with epithelial mesotheliomas. Only recently have markers that are often expressed in mesotheliomas but not in adenocarcinomas been recognized.
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