18521

6-Fmoc-amino-D-luciferin

≥98.5% (TLC)

• Synonym(s): (4S)-2-[6-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-benzothiazolyl]-4,5-dihydro-4-thiazolecarboxylic acid
• Empirical Formula (Hill Notation): C₂₆H₁₉N₃O₄S₂
• CAS Number: 578705-47-2
• Molecular Weight: 501.58
• UNSPSC Code: 12352200
• PubChem Substance ID: 329751683
• NACRES: NA.32

Properties

• assay: ≥98.5% (TLC)
• form: solid
• solubility: DMSO: 1 mg/mL, clear, colorless to almost colorless
• functional group: Fmoc
• storage temp.: −20°C
• SMILES string: O=C(NC1=CC(SC(C2=N[C@](C(O)=O)([H])CS2)=N3)=C3C=C1)OCC4C(C=CC=C5)=C5C6=C4C=CC=C6
• InChI: 1S/C26H19N3O4S2/c30-25(31)21-13-34-23(29-21)24-28-20-10-9-14(11-22(20)35-24)27-26(32)33-12-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-11,19,21H,12-13H2,(H,27,32)(H,30,31)/t21-/m1/s1
• InChI key: ZKXGWUCUGSIASJ-OAQYLSRUSA-N

Description

General description

Amino analog of D-luciferin substrate for firefly luciferase activity. Useful in automated peptide synthesis for incorporation of amino-luciferin into synthetic peptides.

Application

Peptides containing an aminoluciferin become sensitive chemiluminescent substrates for their individual specific peptidase activity when luciferase is added.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable