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14366C

EX-CELL® Advanced CHO Fed-batch Medium

liquid

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Pack SizeSKUAvailabilityPrice
1000 mL

Estimated to ship onMay 21, 2026fromMILWAUKEE

$251.00

About This Item

NACRES:
NA.75
UNSPSC Code:
41161501

$251.00

Estimated to ship onMay 21, 2026Details

​
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sterility

sterile-filtered

Quality Level

500

product line

EX-CELL®

form

liquid

feature

subscription eligible

technique(s)

cell culture | mammalian: suitable (suspension)

components

L-glutamine: no

shipped in

ambient

storage temp.

2-8°C

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This Item
24366C24365C14340C
EX-CELL® Advanced CHO Fed-batch Medium liquid

SAFC

14366C

EX-CELL® Advanced CHO Fed-batch Medium

EX-CELL® Advanced CHO Fed-batch Medium. 20.09 g/L. See information sheet, 24366C @ www.sigmaaldrich.com for hydration instructions.

SAFC

24366C

EX-CELL® Advanced

SAFC

SAFC

24365C

EX-CELL® CD CHO Fusion

SAFC

SAFC

14340C

EX-CELL® 325 PF CHO Serum-Free Medium for CHO Cells

sterility

sterile-filtered

sterility

-

sterility

-

sterility

sterile-filtered

technique(s)

cell culture | mammalian: suitable (suspension)

technique(s)

cell culture | mammalian: suitable (suspension)

technique(s)

cell culture | mammalian: suitable (suspension)

technique(s)

cell culture | mammalian: suitable

form

liquid

form

dry powder

form

dry powder

form

liquid

components

L-glutamine: no

components

-

components

-

components

glucose: 3.45 g/L
L-glutamine: no
NaHCO3: 1.6 g/L
HEPES: 7.5 mM
phenol red: yes

product line

EX-CELL®

product line

EX-CELL®

product line

EX-CELL®

product line

-

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

General description

EX-CELL® AdvancedCHO Fed-batch Medium is chemically-defined and contains no animal derived components. This newest platform from SAFC has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in fed-batch cultures while still allowing for flexibility in the adjustment of protein quality attributes. This contemporary fed-batch platform was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, receptor expression, and glycosylation. This platform contains no hypoxanthine and thymidine, L-glutamine, phenol red or 2-mercaptoethanol (2-ME). This medium is intended to be a part of a fed-batch platform, and used with EX-CELL® Advanced CHO Feed 1 (24367C - with glucose or 24368C - without glucose).

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Donot freeze. Protect from light. Several components of the medium arelight labile and should not be exposed to light for lengthy periods of time.

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000497763
0000497767
0000497767
0000497763
0000415524

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Weiyi Liu et al.
Biotechnology progress, 37(1), e3061-e3061 (2020-08-05)
Antibody-dependent cellular cytotoxicity (ADCC) is the primary mechanism of actions for several marketed therapeutic antibodies (mAbs) and for many more in clinical trials. The ADCC efficacy is highly dependent on the ability of therapeutic mAbs to recruit effector cells such

Articles

EX-CELL® Advanced™ CHO Fed-Batch System – Bioprocessing Technology Institute, Singapore Case Study

In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.

Low-Impurity Iron Sources: Case Studies in EX-CELL® Advanced Medium

Discover how low-impurity iron sources improve reliability and performance in recombinant protein production with EX-CELL® Advanced medium.

Upstream Bioprocessing Feed Strategies and Scalability: A Case Study with Cellvento® ModiFeed Prime COMP

This case study walks through optimizing feed and media for upstream bioprocessing and how it translates to large-scale bioreactors.

CHO Media and Feeds for Optimized Production of Therapeutic Proteins

Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion

See All

Related Content

Cell Culture Media Development for mAbs

Learn more about cell culture media development for mAB development and manufacturing, and the products you need for this step.

Glycosylation Modulation in Fed-batch Production of Therapeutic Proteins

Enhance mAb and recombinant protein performance, efficacy, and stability with precise glycosylation modulation using the Cellvento® ModiFeed platform.

User Guide CHOZN GS Platform

Global Trade Item Number

SKUGTIN
14366C-10X1BC04065274007731
14366C-10X1B04061838437426
14366C-5B04061838437464
14366C-100BD04061838437396
14366C-1BC04065274007748
14366C-100BC04065274007717
14366C-10BAF04065265626217
14366C-50B04061838438294
14366C-100BFS04061838437402
14366C-200BD04061838438270
14366C-100BDAF04065267187815
14366C-2X5B04061838437440
14366C-200BC04065274007755
14366C-20BC04065274007762
14366C-10BC04065274007724
14366C-20B04061838437433
14366C-50BC04065274007779
14366C-1BAF04065267187822
14366C-200BFS04061838438287
14366C-1000ML04061838821973
14366C-10B04061838437419
14366C-1B04061838385628
14366C-200BDAF04065266137514
14366C-500BFS04061838437457

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