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04685

Sigma-Aldrich

Nε-Methyl-L-lysine hydrochloride

≥98.0% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C7H16N2O2 · HCl
CAS Number:
Molecular Weight:
196.68
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.32
assay:
≥98.0% (TLC)
Pricing and availability is not currently available.

Quality Level

assay

≥98.0% (TLC)

optical activity

[α]/D 20.5±1.5°, c = 0.1 in 1 M HCl

storage temp.

2-8°C

SMILES string

Cl.CNCCCC[C@H](N)C(O)=O
Cl.CNCCCC[C@H](N)C(O)=O

InChI

1S/C7H16N2O2.ClH/c1-9-5-3-2-4-6(8)7(10)11;/h6,9H,2-5,8H2,1H3,(H,10,11);1H/t6-;/m0./s1

InChI key

AQELUQTVJOFFBN-RGMNGODLSA-N

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Biochem/physiol Actions

N ε-methyl-L-lysine was identified as a lysine analog with inhibitory effects on the growth and sporulation of Penicillium chrysogenum and benzyl-penicillin formation by mycelia. [1]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Methylated lysines and 3-methylhistidine in myosin: tissue and developmental differences.
G Huszar
Methods in enzymology, 106, 287-295 (1984-01-01)
Agnes M Móricz et al.
Natural product communications, 6(5), 657-660 (2011-05-28)
The influence of monomethylated basic amino acids [NG-monomethyl-L-arginine (MMA) and Nepsilon-monomethyl-L-lysine (MML)] and ozone capturers (indigo carmine, d-limonene) on the antibacterial effect of the mycotoxins aflatoxins B1, B2, G1 and G2 was studied in BioArena, which is a complex bioautographic
B Maras et al.
European journal of biochemistry, 203(1-2), 81-87 (1992-01-15)
The complete amino acid sequence of glutamate dehydrogenase from the thermoacidophilic archaebacterium Sulfolobus solfataricus has been determined. The sequence was reconstructed by automated sequence analysis of peptides obtained after cleavage by trypsin, cyanogen bromide, Staphylococcus aureus V8 protease and pepsin.
A D Sherry et al.
Biochemistry, 23(14), 3181-3185 (1984-07-03)
The carbon- 13 spin-lattice relaxation times and nuclear Overhauser enhancements of the N epsilon-monomethyllysine, N epsilon,N epsilon-dimethyllysine, and N alpha,N alpha-dimethylalanine resonances of 13C-methylated concanavalin A have been measured at three carbon frequencies and compared to the relaxation parameters predicted
M Friedman et al.
The Journal of nutrition, 111(8), 1362-1369 (1981-08-01)
Growth assays using mice on synthetic amino acid diets showed that substituting epsilon-N-methyl-L-lysine, epsilon-N-dimethyl-L-lysine and epsilon-N-trimethyl-L-lysine for lysine resulted in relative replacement values about 1/12, 1/20 and 1/25, respectively, of that obtained with the standard lysine diet. Similar studies showed

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