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53737

Sigma-Aldrich

α-Tri-Calcium phosphate

puriss. p.a., ≥75% α-phase basis (sinterted powder)

Synonym(s):

α-TCP, α-Tricalcium phosphate

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About This Item

Linear Formula:
Ca3(PO4)2
CAS Number:
Molecular Weight:
310.18
EC Number:
MDL number:
UNSPSC Code:
12352300
PubChem Substance ID:

grade

puriss. p.a.

assay

≥75% α-phase basis (sinterted powder)

form

powder

impurities

≤100 mg/kg total sulfur (as SO4) (ICP)
≤50 mg/kg total heavy metals (as lead)

anion traces

chloride (Cl-): ≤50 mg/kg

cation traces

As: ≤0.5 mg/kg
Ba: ≤20 mg/kg
Cd: ≤5 mg/kg
Co: ≤1 mg/kg
Cr: ≤15 mg/kg
Cu: ≤5 mg/kg
Hg: ≤0.5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

SMILES string

[Ca++].[Ca++].[Ca++].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/3Ca.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6

InChI key

QORWJWZARLRLPR-UHFFFAOYSA-H

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Application

α-Tri-Calcium phosphate (α-TCP, α-Tricalcium phosphate) may be used to compose the CaP cement, which is employed for the preparation of the implants.

Analysis Note

Phase Composition (by XRD analysis):
a-TCP: >75%;
other Ca-P phases ß-Tricalcium phosphate, Hydroxylapatite and Calcium pyrophosphate <25%

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Lisa Maria Ehrenfried et al.
Journal of materials science. Materials in medicine, 19(1), 459-466 (2007-07-04)
This paper investigates the effects of alpha-tri-calcium phosphate (alpha-TCP) addition on the properties of polylactide-co-glycolide (PLGA). Samples with additions of 5, 10, 15, 20, 30 and 40 wt% alpha-TCP were prepared via a hotpressing method. Long-term in vitro studies (up
Dennis P Link et al.
Journal of biomedical materials research. Part A, 87(3), 760-769 (2008-01-18)
In this study, the biocompatibility of a calcium phosphate (CaP) cement incorporating poly (D,L-lactic-co-glycolic acid) (PLGA) microparticles was evaluated in a subcutaneous implantation model in rats. Short-term biocompatibility was assessed using pure CaP discs and CaP discs incorporating PLGA microparticles
Dennis P Link et al.
Biomaterials, 27(28), 4941-4947 (2006-06-09)
In this study, the mechanical properties of an implanted calcium phosphate (CaP) cement incorporated with 20wt% poly (dl-lactic-co-glycolic acid) (PLGA) microparticles were investigated in a rat cranial defect. After 2, 4 and 8 weeks of implantation, implants were evaluated mechanically
Muwan Chen et al.
International journal of nanomedicine, 7, 4285-4297 (2012-08-21)
Bone tissue engineering implants with sustained local drug delivery provide an opportunity for better postoperative care for bone tumor patients because these implants offer sustained drug release at the tumor site and reduce systemic side effects. A rapid prototyped macroporous
Timo Brandenburger et al.
Shock (Augusta, Ga.), 42(3), 234-238 (2014-07-01)
Remote ischemic preconditioning (RIPC) is an easily applicable method for protecting the heart against a subsequent ischemia and reperfusion (I/R) injury. However, the exact molecular mechanisms underlying RIPC are unknown. We examined the involvement of microRNAs (miRNAs) and in particular

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