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Y0001630

Prednicarbate for system suitability A

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Prednicarbate, (11β)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione

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10 MG
$236.00

About This Item

Empirical Formula (Hill Notation):
C27H36O8
CAS Number:
Molecular Weight:
488.57
EC Number:
UNSPSC Code:
41116107
NACRES:
NA.24

$236.00


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grade

pharmaceutical primary standard

API family

prednicarbate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O(C1(C2(C(C3C(C4(C(=CC(=O)C=C4)CC3)C)C(C2)O)CC1)C)C(=O)COC(=O)CC)C(=O)OCC

InChI

1S/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3

InChI key

FNPXMHRZILFCKX-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Prednicarbate for system suitability A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Torsten Zuberbier et al.
Dermatology (Basel, Switzerland), 215(4), 325-330 (2007-10-04)
To investigate if pimecrolimus cream 1% reduces the need for steroids in the long-term management of severe pediatric atopic dermatitis (AD). A total of 184 pediatric patients (aged 2-17 years) with a history of severe AD according to Rajka and
R Foelster-Holst et al.
Dermatology (Basel, Switzerland), 212(1), 66-69 (2005-12-02)
The wet-wrap treatment has been reported to be beneficial in acute episodes of atopic dermatitis (AD) skin lesions. The efficacy of topical corticosteroid prednicarbat with and without additional wet-wrap dressing was investigated in a prospective, randomized and controlled study. In
J Reuter et al.
Skin pharmacology and physiology, 21(2), 106-110 (2008-02-07)
Aloe vera is a natural product that is frequently used in soothing skin care products such as aftersun lotions. In the present study we aimed to explore the anti-inflammatory potential of a highly concentrated A. vera gel in the UV
Yücel Baspinar et al.
International journal of pharmaceutics, 430(1-2), 247-252 (2012-04-11)
The surface of all tissues, including the stratum corneum, carries a negative charge. Following that fact it is assumed that a positively charged topical formulation could lead to an enhanced penetration because of an increased interaction with the negative charge
Aditya K Gupta et al.
Journal of drugs in dermatology : JDD, 3(5), 553-556 (2004-11-24)
Prednicarbate is a non-halogenated, double-ester derivative of prednisolone that has become of interest for the treatment of inflammatory skin diseases, for example atopic dermatitis. In the past, topical steroids have been a popular choice for treating these diseases; however, the

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