Y0001553

Ciclesonide

European Pharmacopoeia (EP) Reference Standard

• Empirical Formula (Hill Notation): C₃₂H₄₄O₇
• CAS Number: 126544-47-6
• Molecular Weight: 540.69
• MDL number: MFCD00866004
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• biological source: synthetic
• grade: pharmaceutical primary standard
• agency: EP
• API family: ciclesonide
• packaging: pkg of 150 mg
• manufacturer/tradename: EDQM
• storage condition: protect from light
• color: white
• bp: 665.0 °C/1.333 hPa (1229.0°F)
• mp: 209-211 °C (408—412°F)
• solubility: water: <0.1 g/L; acetone: soluble; ethanol: soluble
• density: 1.23 g/cm³ at 20 °C (1.333 hPa)
• application(s): pharmaceutical (small molecule)
• format: neat
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: C[C@@]12C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@]5([H])[C@]4(O[C@@](C6CCCCC6)([H])O5)C(COC(C(C)C)=O)=O)=CC(C=C1)=O
• InChI: 1S/C32H44O7/c1-18(2)28(36)37-17-25(35)32-26(38-29(39-32)19-8-6-5-7-9-19)15-23-22-11-10-20-14-21(33)12-13-30(20,3)27(22)24(34)16-31(23,32)4/h12-14,18-19,22-24,26-27,29,34H,5-11,15-17H2,1-4H3/t22-,23-,24-,26+,27+,29+,30-,31-,32+/m0/s1
• InChI key: LUKZNWIVRBCLON-GXOBDPJESA-N

Description

General description

Ciclesonide is a new-generation, non-halogenated glucocorticoid. It is a prodrug that releases an active primary metabolite, ciclesonide−active principle (CIC-AP), on enzymatic cleavage.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable