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Enilconazole

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Imazalil, 1-[2-(Allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole

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About This Item

Empirical Formula (Hill Notation):
C14H14Cl2N2O
CAS Number:
35554-44-0
Molecular Weight:
297.18
Beilstein/REAXYS Number:
545683
MDL number:
MFCD00055331
UNSPSC Code:
41116107
PubChem Substance ID:
329830860
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

enilconazole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Clc1ccc(C(Cn2ccnc2)OCC=C)c(Cl)c1

InChI

1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2

InChI key

PZBPKYOVPCNPJY-UHFFFAOYSA-N

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General description

Enilconazole is a topically active imidazole derivative, for veterinary application in poultry against Aspergillus sp., and in dogs, cattle, and horses for the treatment of dermatophytosis.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Enilconazole may be used as a reference compound to analyze the effect of enilconazole during the surgical treatment of canine nasal aspergillosis by rhinotomy combined with enilconazole infusion and oral itraconazole.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Treatment of canine nasal aspergillosis with enilconazole.
Sharp N J, et al.
Journal of Veterinary Internal Medicine, 7(1), 40-43 (1993)
Surgical treatment of canine nasal aspergillosis by rhinotomy combined with enilconazole infusion and oral itraconazole.
Claeys S, et al.
The Journal of Small Animal Practice, 47(6), 320-324 (2006)
Liwei An et al.
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Infection with influenza A virus is still a global concern since it causes significant mortality, morbidity and economic loss. New burst pandemics and rapid emergence of drug-resistance strains in recent years call for novel antiviral therapies. One promising way to
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Drug-induced gene-expression profiles that invert disease profiles have recently been illustrated to be a starting point for drug repositioning. In this study, we validate this approach and focus on prediction of novel drugs for colorectal cancer, for which there is

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