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Y0000108

Trihexyphenidyl hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(±)-α-Cyclohexyl-α-phenyl-1-piperidinepropanol hydrochloride

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80 MG
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80 MG
$164.00

About This Item

Empirical Formula (Hill Notation):
C20H31NO · HCl
CAS Number:
52-49-3
Molecular Weight:
337.93
MDL number:
MFCD00058212
UNSPSC Code:
41116107
PubChem Substance ID:
329830848
NACRES:
NA.24

$164.00

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grade

pharmaceutical primary standard

API family

trihexyphenidyl hydrochloride

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.OC(CCN1CCCCC1)(C2CCCCC2)c3ccccc3

InChI

1S/C20H31NO.ClH/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21;/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2;1H

InChI key

QDWJJTJNXAKQKD-UHFFFAOYSA-N

Gene Information

human ... CHRM1(1128)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Trihexyphenidyl hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

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Shui-Qing Zheng et al.
Fa yi xue za zhi, 27(4), 271-273 (2011-09-15)
To develop a method to measure trihexyphenidyl, chlorpromazine and clozapine in human blood with GC-MS. The specimens were alkalized (pH > 10) and extracted with V (benzene):V(ethyl acetate) = 1:1, and qualitatively analyzed using GC-MS-Full Scan with internal standard SKF525A.
Alex Pollock et al.
The Cochrane database of systematic reviews, (10)(10), CD008389-CD008389 (2011-10-07)
Eye movement disorders may affect over 70% of stroke patients. These eye movement disorders can result in difficulty maintaining the normal ocular position and difficulty moving the eyes appropriately. The resulting functional disabilities include a loss of depth perception, reduced
Clinical reasoning: A 13-year-old boy presenting with dystonia, myoclonus, and anxiety.
Joanna S Blackburn et al.
Neurology, 78(11), e72-e76 (2012-03-14)
Archana Verma et al.
The Journal of the Association of Physicians of India, 59, 526-527 (2011-09-06)
We report a 42 year-old woman with 6 month history of isolated lingual dystonia induced during speaking and was treated with anticholinergic drug. She experienced a marked improvement in her abnormal tongue movements. Primary lingual dystonia is a rare presentation.
Joana Damásio et al.
Movement disorders : official journal of the Movement Disorder Society, 26(4), 679-684 (2011-04-21)
The co-occurrence of tics and dystonia as an idiopathic condition has only rarely been reported. We report a series of patients with tics and persistent dystonia, with the aim of determining the prevalence and clinical characteristics of this syndrome. Analysis
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