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Y0000022

Sumatriptan succinate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate, GR-43175

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50 MG
$236.00

$236.00

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50 MG
$236.00

About This Item

Empirical Formula (Hill Notation):
C14H21N3O2S · C4H6O4
CAS Number:
103628-48-4
Molecular Weight:
413.49
MDL number:
MFCD00902856
UNSPSC Code:
41116107
PubChem Substance ID:
329830818
NACRES:
NA.24

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grade

pharmaceutical primary standard

API family

sumatriptan

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

Storage temp.

−20°C

SMILES string

OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1

InChI

1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)

Inchi Key

PORMUFZNYQJOEI-UHFFFAOYSA-N

Gene Information

human ... HTR1B(3351) , HTR1D(3352)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sumatriptan succinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Sumatriptan succinate is a 5-HT1 serotonin receptor agonist.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

1642201

Sumatriptan succinate, United States Pharmacopeia (USP) Reference Standard

1642212

Sumatriptan Succinate Related Compound A, United States Pharmacopeia (USP) Reference Standard

Y0000026

Sumatriptan impurity mixture, European Pharmacopoeia (EP) Reference Standard

Y0000027

Sumatriptan for system suitability, European Pharmacopoeia (EP) Reference Standard

1642154

Sumatriptan, United States Pharmacopeia (USP) Reference Standard

1642256

Sumatriptan succinate Related Impurities, United States Pharmacopeia (USP) Reference Standard

1642223

Sumatriptan succinate Related Compound C, United States Pharmacopeia (USP) Reference Standard

BP950

Sumatriptan succinate, British Pharmacopoeia (BP) Reference Standard

PHR2580

Sumatriptan Succinate, pharmaceutical secondary standard, certified reference material

PHR2914

Sumatriptan Succinate Related Compound C, certified reference material, pharmaceutical secondary standard

Pictograms

Health hazard
GHS08

signalword

Warning

Hazard Classifications

Aquatic Chronic 3 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Y Sekino et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 24(12), 1083-e564-1083-e564 (2012-08-14)
Oral sumatriptan administration has been reported to delay gastric emptying after liquid meals. The aim of this study was to determine whether delayed gastric emptying is caused by enhanced gastric accommodation, impaired antral contractions, or both using ultrasonography. Ten healthy
Luigi Alberto Pini et al.
The journal of headache and pain, 13(8), 669-675 (2012-10-12)
In this study, we compared the efficacy and tolerability of the combination of paracetamol 1,000 mg + caffeine 130 mg (PCF) with sumatriptan 50 mg (SUM) in migraine attacks. This was a multi-center randomized double-blind, double-dummy, cross-over controlled trial. The
Maria Luisa González-Rodríguez et al.
Journal of pharmaceutical sciences, 101(10), 3845-3863 (2012-07-19)
Niosomes formulated from different nonionic surfactants (Span® 60, Brij® 72, Span® 80, or Eumulgin® B 2) with cholesterol (CH) molar ratios of 3:1 or 4:1 with respect to surfactant were prepared with different sumatriptan amount (10 and 15 mg) and
Shree G Sharma et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 61(2), 326-329 (2012-12-05)
Renal cortical infarction is a rare cause of acute kidney injury that results from inadequate blood flow to the kidney, most commonly as a consequence of thrombotic or embolic occlusion of the renal artery or profound hypoperfusion. We report the
Nahid Shahabadi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 99, 18-22 (2012-10-09)
The interaction of native calf thymus DNA with sumatriptan(1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide) at physiological pH was studied by spectrophotometry, circular dichroism, voltammetry and viscosimetric techniques. Sumatriptan molecule intercalated between base pairs of DNA, showed by a sharp increase in specific viscosity of DNA.
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